Dr Jorge Del-Pozo

The Royal (Dick) School of Veterinary Studies/The Roslin Institute

Research Interests

My main research interest is in piscine pathology. More specifically I have a strong interest on the research of fish diseases affecting aquaculture species, and promoting scientific understanding that can be translated to the effective control of these diseases.

My basic approach to this research is the use of techniques including histopathology, immunohistochemistry, bacteriology, virology, and molecular diagnostic tools, interpreted in the context of genomic studies of the host and aetiological agent. 

I also have an strong interest in comparative research using zebrafish as a model, and have worked in the development of a model of steroidogenesis using zebrafish.

Last but not least, as a working diagnostic veterinary pathologist, I have a strong interest in the pathogenesis and gross, microscopic and ultrastructural presentation of disease in all animal species, as well as clinical research in collaboration with my veterinary colleagues at the animal hospitals of the EBVC.

Selected Publications

  • Patricia Noguera, Bertrand Collet, Matthias Klinger, Hristo Örün, Jorge Del Pozo. 2018. Use of Salmon Cardiac Primary Cultures (SCPCs) of different genotypes for comparative kinetics of mx expression, viral load and ultrastructure pathology, after infection with Salmon Pancreas Disease Virus (SPDV). Fish & shellfish immunology Vol: 72 Pages: 181-186. More»
  • Patricia A Noguera, Bianka Grunow, Matthias Klinger, Katherine Lester, Bertrand Collet, Jorge Del-Pozo. 2017. Atlantic salmon cardiac primary cultures: An in vitro model to study viral host pathogen interactions and pathogenesis. PLoS One Vol: 12 Pages: e0181058. More»
  • Bastiaan Vliegenthart, Chunmin Wei, Charlotte Buckley, Cécile Berends, Carmelita de Potter, Sarah Schneemann, Jorge Del-Pozo, Carl Tucker, John Mullins, David Webb, James Dear. 2017. Characterization of triptolide-induced hepatotoxicity by imaging and transcriptomics in a novel zebrafish model. Toxicological Sciences Vol: 159 Pages: 380-391. More»
  • Wesam Gamal, Philipp Treskes, Kay Samuel, Gareth Sullivan, Richard Siller, Vlastamil Srsen, Frances Morgan, Anna Bryans, Ada Kozlowska, Andreas Koulovasilopoulos, Ian Underwood, Stewart Smith, Jorge Del-Pozo, Sharon Moss, Alexandra I. Thompson, Neil Henderson, Peter Hayes, John Plevris, Pierre Bagnaninchi, Leonard Nelson. 2017. Low-dose acetaminophen induces early disruption of cell-cell tight junctions in human hepatocytes and mouse liver. Scientific Reports Vol: 7 Pages: 37541. More»
  • Charlotte Avanzi, Jorge Del-Pozo, Andrej Benjak, Karen Stevenson, Victor R. Simpson, Philippe Busson, Joyce McLuckie, Chloé Loiseau, Colin Lawton, Janne Schoening, Darren Shaw, Jérémie Piton, Lucio Vera-Cabrera, Jesùs S. Velarde-Felix, Fergal McDermott, Stephen V. Gordon, Stewart T. Cole, Anna Meredith. 2016. Red squirrels in the British Isles are infected with leprosy bacilli. Science Vol: 354 Pages: 744-747. More»
  • Jorge Del-Pozo, N. Mishra, R. Kabuusu, S. Cheetham, A. Eldar, E. Bacharach, W. I. Lipkin, H. W. Ferguson. 2016. Syncytial Hepatitis of Tilapia (Oreochromis niloticus L.) is Associated With Orthomyxovirus-Like Virions in Hepatocytes. Veterinary Pathology. More»
  • Eran Bacharach, Nischay Mishra, Thomas Briese, Michael C Zody, Japhette Esther Kembou Tsofack, Rachel Zamostiano, Asaf Berkowitz, James Ng, Adam Nitido, André Corvelo, Nora C Toussaint, Sandra Cathrine Abel Nielsen, Mady Hornig, Jorge Del Pozo, Toby Bloom, Hugh Ferguson, Avi Eldar, W Ian Lipkin. 2016. Characterization of a Novel Orthomyxo-like Virus Causing Mass Die-Offs of Tilapia. mBio Vol: 7. More»
  • A. Meredith, Jorge Del-Pozo, S. Smith, E. Milne, K. Stevenson, J. Mcluckie. 2014. Leprosy in red squirrels in Scotland. Veterinary Record Vol: 175 Pages: 285-286. More»
  • Sebastian Pieperhoff, Kathryn S Wilson, James Baily, Kim de Mora, Sana Maqsood, Sharron Vass, Jonathan Taylor, Jorge Del-Pozo, Calum A MacRae, John J Mullins, Martin A Denvir. 2014. Heart on a plate: histological and functional assessment of isolated adult zebrafish hearts maintained in culture. PLoS One Vol: 9 Pages: e96771. More»
  • A D B Vliegenthart, Carl Tucker, Jorge Del-Pozo, J W Dear. 2014. Zebrafish as model organisms for studying drug induced liver injury. British Journal of Clinical Pharmacology. More»
  • Adriaan D B Vliegenthart, Philip Starkey Lewis, Carl S Tucker, Jorge Del-Pozo, Sebastein Rider, Daniel J Antoine, Valérie Dubost, Magdalena Westphal, Pierre Moulin, Matthew A Bailey, Jonathan G Moggs, Chris E Goldring, B Kevin Park, James W Dear. 2014. Retro-orbital Blood Acquisition Facilitates Circulating microRNA Measurement in Zebrafish with Paracetamol Hepatotoxicity. Zebrafish Vol: 11. More»
  • Hugh W. Ferguson, Richard Kabuusu, Sussan Beltran, Eduardo Reyes, J.A. Lince, Jorge Del-Pozo. 2013. Syncytial hepatitis of farmed tilapia, Oreochromis niloticus (L.): a case report. Journal of Fish Diseases Vol: Early View. More»
  • Sebastien A. Rider, Carl S. Tucker, Jorge del-Pozo, Kirsten N. Rose, Calum A. MacRae, Matthew A. Bailey, John J. Mullins. 2012. Techniques for the in vivo assessment of cardio-renal function in zebrafish (Danio rerio) larvae. Journal of Physiology Vol: 590 Pages: 1803-1809. More»