Professor Ross Fitzgerald

The Roslin Institute

Research Interests

The laboratory is focused on the evolution and pathogenesis of clinically important species of Staphylococci including the major human and animal pathogen Staphylococcus aureus. We are currently using a range of molecular and genomic tools to understand the evolutionary origin and the molecular basis of staphylococcal diseases. A major goal is to translate our findings into new diagnostic, preventive and therapeutic approaches to controlling infections.

Selected Publications

  • Laura Spoor, Paul McAdam, Lucy A. Weinert, Andrew Rambaut, Henrik Hasman, Frank M. Aarestrup, Angela M. Kearns, Anders F. Larsen, Robert L. Skov, Ross Fitzgerald. 2013. Livestock origin for a human pandemic clone of community-associated MRSA. mBio Vol: 13. More»
  • Paul McAdam, J Ross Fitzgerald and 35 others. 2013. A genomic portrait of the emergence, evolution, and global spread of a methicillin resistant Staphylococcus aureus pandemic. Genome Research Vol: 23 Pages: 653-664. More»
  • P. R. McAdam, K. E. Templeton, G. F. Edwards, M. T. Holden, E. J. Feil, D. M. Aanensen, H. J. Bargawi, B. G. Spratt, S. D. Bentley, J. Parkhill, M. C. Enright, A. Holmes, E. K. Girvan, P. A. Godfrey, M. Feldgarden, A. M. Kearns, A. Rambaut, D. A. Robinson, J. R. Fitzgerald. 2012. Molecular tracing of the emergence, adaptation, and transmission of hospital-associated methicillin-resistant Staphylococcus aureus. Proceedings of the National Academy of Sciences Vol: 109 Pages: 9107-9112. More»
  • D. Viana, J. Blanco, M.A. Tormo-Mas, L. Selva, C.M. Guinane, R. Baselga, J.M. Corpa, I. Lasa, R.P. Novick, J.R. Fitzgerald, J.R. Penades. 2010. Adaptation of Staphylococcus aureus to ruminant and equine hosts involves SaPI-carried variants of von Willebrand factor-binding protein. Molecular Microbiology Vol: 77 Pages: 1583-1594. More»
  • Bethan V Lowder, Caitriona M Guinane, Nouri L Ben Zakour, Lucy A Weinert, Andrew Conway-Morris, Robyn A Cartwright, A John Simpson, Andrew Rambaut, Ulrich NĂ¼bel, J Ross Fitzgerald. 2009. Recent human-to-poultry host jump, adaptation, and pandemic spread of Staphylococcus aureus. Proceedings of the National Academy of Sciences Vol: 106 Pages: 19545-50. More»
  • G.J. Wilson, K.S. Seo, R.A. Cartwright, T. Connelley, O.N. Chuang-Smith, J.A. Merriman, C.M. Guinane, J.Y. Park, G.A. Bohach, P.M. Schlievert, W.I. Morrison, J.R. Fitzgerald. 2011. A Novel Core Genome-Encoded Superantigen Contributes to Lethality of Community-Associated MRSA Necrotizing Pneumonia. PLoS Pathogens Vol: 7 Pages: e1002271. More»
  • C. M. Guinane, D. E. Sturdevant, L. Herron-Olson, M. Otto, D. S. Smyth, A. E. Villaruz, V. Kapur, P. J. Hartigan, C. J. Smyth, J. R. Fitzgerald. 2008. Pathogenomic analysis of the common bovine Staphylococcus aureus clone (ET3): emergence of a virulent subtype with potential risk to public health. The Journal of Infectious Diseases Vol: 197 Pages: 205-213. More»